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p53 status of newly established acute myeloid leukaemia cell lines

✍ Scribed by Zheng, A; Castren, K; Säily, M; Savolainen, E-R; Koistinen, P; Vähäkangas, K


Book ID
110000933
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
276 KB
Volume
79
Category
Article
ISSN
0007-0920

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Screening the p53 status of human cell l
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We have screened the p53 status of 156 human cell lines, including 142 tumor cell lines from 27 different tumor types and 14 cell lines from normal tissues by using functional analysis of separated alleles in yeast. This assay enables us to score wild-type p53 expression on the basis of the ability