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p53 status in radiation-induced soft-tissue sarcomas

✍ Scribed by Helge Taubert; Axel Meye; Matthias Bache; Raoul Hinze; Hans-Jürgen Holzhausen; Hannelore Schmidt; Friedrich-Wilhelm Rath; Jürgen Dunst; Peter Würl

Book ID
105701426
Publisher
Springer
Year
1998
Tongue
German
Weight
583 KB
Volume
174
Category
Article
ISSN
0179-7158

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No p16INK4A/CDKN2/MTS1 mutations indepen
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The p16 INK4A /CDKN2/MTS1 gene encodes a specific inhibitor of cyclin-dependent kinases (CDKs) 4 and 6. This study investigates p16 INK4A gene status and expression in mesenchymal tumours, in particular soft tissue sarcomas (STSs). Employing non-radioactive polymerase chain reaction-single strand co