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p53 Status does not affect photodynamic cell killing induced by hypericin

✍ Scribed by H. B. Lee; A. S. H. Ho; S. H. Teo


Book ID
105992260
Publisher
Springer
Year
2005
Tongue
English
Weight
331 KB
Volume
58
Category
Article
ISSN
0344-5704

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We introduced the mutant p53 zene (codon 273Ar9-His) into human fibroblasts (SUSM-I ceils) previously immortalized with 4-nitroquinoline I -oxide (4NQO) and obtained 2 clonal cell lines (SUSM-I /p53-I and SUSM-l/p53-6) expressing the mutant p53. Since the genetic background of SUSM-l/p53 is the same