p53 protein accumulation as a prognostic marker in sporadic colorectal cancer
β Scribed by Yuan-Tzu Lan; Shih-Ching Chang; Anna Fen-Yau Li; Tzu-Chen Lin; Wei-Shone Chen; Jeng-Kai Jiang; Shung-Haur Yang; Huann-Sheng Wang; Jen-Kou Lin
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 146 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0179-1958
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The prognostic value of p53 protein accumulation in breast cancer, especially as detected by methods other than immunohistochemistry, has not been established unequivocally. A sensitive immunofluorometric assay of p53 protein employing DO-1 and CM-1 antibodies was used in this study to assay extract
Background and Objectives: Expression of S100A4, a small calcium-binding protein, in breast, oesophagus and gall bladder cancers is shown to be associated with adverse clinical outcome. We retrospectively examined the correlation of S100A4 expression and outcome in patients with colorectal cancer. M
Only half of colorectal-cancer patients elicit serum antibodies in response to intratumoral p53-gene mutations. Our study was designed to compare cellular events (p53-protein accumulation and gene mutations) with the presence of circulating anti-p53 antibodies (p53-Ab). Thirty-five colorectalcancer
## Abstract ## Background Cyclooxygenase (COX)β2 is believed to be an important enzyme related to the pathogenesis of colorectal cancer (CRC). p53 has been reported to be a negative regulator of COXβ2 expression in in vitro studies. The aim of this study was to investigate COXβ2 expression and its