## Abstract Human papillomavirus (HPV) infects the squamous epithelial cells of oral cavity and cervix leading to formation of warts that develops into the cancer. Human papillomavirus (HPV)β16 and 18 encode E6 oncoprotein, which binds to and induces degradation of the tumour suppressor protein p53
β¦ LIBER β¦
P53 (Pro72Arg) polymorphism associated with the risk of oral squamous cell carcinoma in gutka, niswar and manpuri addicted patients of Pakistan
β Scribed by Saleem, Saima; Azhar, Abid; Hameed, Abdul; Khan, Mansoor Ahmed; Abbasi, Zubair Ahmed; Qureshi, Navid Rashid; Ajmal, Muhammad
- Book ID
- 122061959
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- English
- Weight
- 932 KB
- Volume
- 49
- Category
- Article
- ISSN
- 1368-8375
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Around 50% of head and neck cancers are known to have aberrations of the p53 gene. Overexpression of the mutant p53 protein can induce a specific humoral response in cancer patients. Matched saliva, serum, and tissue samples from 26 patients with histologically confirmed oral squamous and verrucous