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p53 Nuclear Accumulation and Bcl-2 Expression in Contiguous Adenomatous Components of Colorectal Adenocarcinomas Predict Aggressive Tumor Behavior

โœ Scribed by Shanmugam, C.; Katkoori, V. R.; Jhala, N. C.; Grizzle, W. E.; Siegal, G. P.; Manne, U.

Book ID
125848952
Publisher
Histochemical Society
Year
2007
Tongue
English
Weight
174 KB
Volume
56
Category
Article
ISSN
0022-1554

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The products of bcl-2 and p53 genes are involved in the regulation of apoptosis and proliferation and have been associated with prognosis in several malignancies, including colorectal adenocarcinoma. Although 2 European studies have reported a prognostic significance of Bcl-2 expression in colorecta