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p53 Mutations and Survival in Stage I Non-Small-Cell Lung Cancer: Results of a Prospective Study

โœ Scribed by Ahrendt, S. A.; Hu, Y.; Buta, M.; McDermott, M. P.; Benoit, N.; Yang, S. C.; Wu, L.; Sidransky, D.

Book ID
125487955
Publisher
Oxford University Press
Year
2003
Tongue
English
Weight
433 KB
Volume
95
Category
Article
ISSN
0027-8874

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Validated markers are needed to identify operable lung cancer patients with poor prognosis. About one-half of nonsmall-cell lung cancers (NSCLCs) carry a mutation in the p53 tumor-suppressor gene. We examined 101 NSCLC patients for surgical stage, completeness of resection, tobacco smoking, asbestos