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p53 Mutations and protein overexpression in primary colorectal cancer and its liver metastasis

✍ Scribed by Yang Yang; Wei Yuan; Bing-Ji Wen


Publisher
Chinese Anti-Cancer Association
Year
2000
Tongue
English
Weight
332 KB
Volume
12
Category
Article
ISSN
1000-9604

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Only half of colorectal-cancer patients elicit serum antibodies in response to intratumoral p53-gene mutations. Our study was designed to compare cellular events (p53-protein accumulation and gene mutations) with the presence of circulating anti-p53 antibodies (p53-Ab). Thirty-five colorectalcancer