## Abstract Elevated aflatoxin B~1~‐albumin adducts (AFB~1~‐Alb) have been associated with an increased risk for HCC development. However, there are no studies in humans, correlating albumin adducts in blood with liver DNA adducts. Forty frozen tumor tissues and 39 paired plasma samples from HCC pa
p53 mutations and aflatoxin B1 exposure in hepatocellular carcinoma patients from thailand
✍ Scribed by Monica C. Hollstein; Christopher P. Wild; Françoise Bleicher; Sopa Chutimataewin; Curtis C. Harris; Andpetcharin Srivatanakul; Ruggero Montesano
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- French
- Weight
- 667 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0020-7136
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
afflicted with both HCV and MC. Both Misiani et a1 and Lunel et be 'Ommended for their the mystery surrounding this fascinating group of patients. cryoglobulinemia patients: a randomized, crossover-controlled trial.
Aflatoxins are well-known animal hepatocarcinogens, but the association between aflatoxins and human hepatocellular carcinoma remains to be elucidated. A study method consisting of indirect immunofluorescence assay combined with densitometry was developed to quantitate aflatoxin B1 DNA adducts in sm
The cyclin-dependent kinase inhibitor p21/WAF1 is regulated by p53-dependent and p53-independent pathways. In addition, p21/WAF1 binds with proliferating cell nuclear antigen (PCNA) and inhibits the action of PCNA. To investigate the possible role of p21/WAF1 in human hepatocellular carcinomas (HCCs
## Abstract β‐Catenin plays a key role in the Wnt signaling pathway, and mutations of __CTNNB1__, the gene that encodes β‐catenin, have been identified in about one‐fourth of human hepatocellular carcinomas from regions of low aflatoxin B1 exposure. In this study 62 hepatocellular carcinomas (HCCs)