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p53-derived peptide inhibits human pancreatic cancer cell growth

✍ Scribed by Wilbur B. Bowne; Vadim Shtreyler; Michael Vishnevetsky; Martin Bluth; Michael Zenilman; Josef Michl; Matthew Pincus

Book ID
113677357
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
47 KB
Volume
203
Category
Article
ISSN
1072-7515

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## Abstract PNC‐28 is a p53 peptide from its mdm‐2‐binding domain (residues 17–26), which contains the penetratin sequence enabling cell penetration on its carboxyl terminal end. We have found that this peptide induces necrosis, but not apoptosis, of a variety of human tumor cell lines, including s

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