P53 and bcl-2 assessment in serous ovarian carcinoma
β Scribed by J.E. PALMER; L.J. SANT CASSIA; C.J. IRWIN; A.G. MORRIS; T.P. ROLLASON
- Book ID
- 109086201
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 98 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1048-891X
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π SIMILAR VOLUMES
## Abstract Serous ovarian carcinoma comprises a clinically heterogenous group of tumors, and molecular markers stratifying patients into clinically meaningful subgroups are needed. Numerous markers have been evaluated, but none of them has yet been routinely incorporated into clinical practice. Pr
## BACKGROUND. Although p53 gene mutation frequently is observed in ovarian carcinoma, the function of the p53 gene in chemosensitivity has not been defined conclusively. The objective of the current study was to elucidate the relation between chemotherapy-induced apoptosis through the p53 pathway