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P52: Microarray-CGH analysis of the 8q22–q23, 13q21–q31 and 20q amplicons associated with colorectal cancer progression

✍ Scribed by Beatriz Carvalho; Cindy Postma; Sandra Mongera; Bauke Ylstra; Gerrit A. Meijer


Book ID
116432926
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
48 KB
Volume
48
Category
Article
ISSN
1769-7212

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## Abstract The chromosomal region 11q13 is amplified in 15–20% of breast cancers; an event not only associated with estrogen receptor (ER) expression but also implicated in resistance to endocrine therapy. Coamplifications of the 11q13 and 8p12 regions are common, suggesting synergy between the am