P5. Changes in the phosphoinositide system are associated with 1,25(OH)2D3 induced differentiation in U937 cells

1,25-dihydroxyvitamin D3-induced retarda

1,25-dihydroxyvitamin D3-induced retardation of the G2/M traverse is associated with decreased levels of p34cdc2 in HL60 cells

✍ Lawrence E. Harrison; Qing Mei Wang; George P. Studzinski 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 233 KB 👁 1 views

Cellular differentiation of neoplastic cells after exposure to 1,25-dihydroxyvitamin D 3 (1,25 D 3 ) is accompanied by altered cell cycle regulation. In previous studies, blocks in both G 1 /S and G 2 /M checkpoints have been observed in 1,25D 3 -treated HL60 cells, but the mechanism of the 1,25D 3