P4C33 - Maternal, embryonic and fetal effects of parenterally administered epidermal growth factor (EGF) in rats
✍ Scribed by S. Alvarez; A. Díaz; J. Berlanga
- Book ID
- 119540570
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 141 KB
- Volume
- 95
- Category
- Article
- ISSN
- 0378-4274
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Epidermal growth factor (EGF) causes gender-and development-specific changes in fetal lung surfactant synthesis. We hypothesized that the effects of EGF on development of surfactant synthesis are related to effects on EGF receptor (EGF-R) expression. We prepared sex-specific fetal rabbit lung organ
## Abstract ## BACKGROUND 2,3,7,8‐Tetrachlorodibenzo‐p‐dioxin (TCDD) is teratogenic in mice, producing cleft palate (CP). TCDD exposure disrupts expression of epidermal growth factor (EGF) receptor, EGF, and transforming growth factor‐α (TGFα) in the palate and affects proliferation and differenti