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P450 3A activity and cyclosporine dosing in kidney and heart transplant recipients

✍ Scribed by Turgeon, D Kim; Leichtman, Alan B; Lown, Kenneth S; Normolle, Daniel P; Deeb, G Michael; Merion, Robert M; Watkins, Paul B

Book ID
109845340
Publisher
Nature Publishing Group
Year
1994
Tongue
English
Weight
631 KB
Volume
56
Category
Article
ISSN
0009-9236

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Importance of cytochrome P-450IIIA activ
Importance of cytochrome P-450IIIA activity in determining dosage and blood levels of FK 506 and cyclosporine in liver transplant recipients
✍ Yilmaz Cakaloglu; J. Michael Tredger; John Devlin; Roger Williams πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 English βš– 727 KB

We have investigated the importance of cytochrome P-45OIIIA enzyme activity in influencing dosage of the immunosuppressive drugs FK 506 and cyclosporine after liver transplantation. Cytochrome P-45OIIIA enzyme activity in uiuo was measured 1 yr postoperatively in 37 stable orthotopic liver graft rec