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P4-378 The effect of a-beta immunization on blood-brain barrier integrity in the TG2576 AD model mouse

✍ Scribed by Dickstein, Dara L.; Jeffries, Andrew R.; Jefferies, Wilfred A.


Book ID
123310107
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
160 KB
Volume
25
Category
Article
ISSN
0197-4580

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In the present study, the vasomotor effects of nicotine, its interaction with local chemical factors and norepinephrine, and its effects on the permeability of the blood-brain barrier (BBB) were investigated. Using perivascular microapplication, 10-6 M nicotine was found not to exert a vasomotor eff