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P4-353 Targeting megalin as a possible therapeutic alternative in Alzheimer's disease

✍ Scribed by Carro, Eva


Book ID
123108875
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
158 KB
Volume
25
Category
Article
ISSN
0197-4580

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The pathology of Alzheimer's disease (AD) is characterized by cerebral atrophy in frontal, temporal, and parietal regions, with senile plaques, dystrophic neurites, and neurofibrillar tangles within defined areas of the brain. Another characteristic of AD is regional hypometabolism in the brain. Thi