𝔖 Bobbio Scriptorium
✦   LIBER   ✦

P4-283 Endoproteolysis of presenilin-1 is an intramolecular autocatalytic event

✍ Scribed by Brunkan, Anne L.; Martinez, Maribel; Goate, Alison M.

Book ID
123131947
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
312 KB
Volume
25
Category
Article
ISSN
0197-4580

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Caspase cleavage of exon 9 deleted prese
Caspase cleavage of exon 9 deleted presenilin-1 is an early event in apoptosis induced by calcium ionophore A 23187 in SH-SY5Y neuroblastoma cells
✍ Bogdan O. Popescu; Angel Cedazo-Minguez; Laurentiu M. Popescu; Bengt Winblad; Ri 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 345 KB 👁 1 views

## Abstract Presenilins (PSs) are mutated in a majority of familial Alzheimer disease (FAD) cases. Mutated PSs may cause FAD by a number of pro‐apoptotic mechanisms, or by regulating γ‐secretase activity, a protease involved in β‐amyloid precursor protein processing to the neurotoxic β‐amyloid pept