P4-242: Identification of signaling molecules transducing NMDA receptor signals to MAPK/ERK in neurons

p75 Neurotrophin receptor is implicated

p75 Neurotrophin receptor is implicated in the ability of neurotrophin-3 to negatively modulate activated ERK1/2 signaling in TrkA-expressing adult sensory neurons

✍ Tracy D. Wilson-Gerwing; Jayne M. Johnston; Valerie M.K. Verge 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 643 KB

## Abstract Neurotrophin‐3 (NT‐3) can negatively modulate trkA and associated phenotype in intact sensory neurons, while positively regulating trkC and associated phenotype. How NT‐3 effects this response is not clear. Whether NT‐3 exerts a differential influence on levels of activated ERK1/2 signa