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P4-176: Proteomics determined glycoproteome in mild cognitive impairment, early Alzheimer's disease, and late-stage Alzheimer's disease hippocampus and inferior parietal lobule

โœ Scribed by Owen, Joshua B.; Dominico, Fabio; Perluigi, Marzia; Sultana, Rukhsana; Butterfield, D. Allan


Book ID
122710900
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
52 KB
Volume
4
Category
Article
ISSN
1552-5260

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## Abstract Lectin affinity chromatography is a powerful separation technique that fractionates proteins by selectively binding to specific carbohydrate moieties characteristic of protein glycosylation type. Wheat germ agglutinin (WGA) selectively binds terminal Nโ€acetylglucosamine (Oโ€GlcNAc) and s