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P.3.d.021 Differential gene expressions in frontal cortex of rats induced by chronic release of risperidone

✍ Scribed by K. Kim; H.O. Chae; W.M. Bark; K.U. Lee; D.J. Kim; H.J. Seo; Y.S. Woo


Book ID
118594170
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
58 KB
Volume
17
Category
Article
ISSN
0924-977X

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After 5 days of continuous treatment with d-amphetamine base in doses greater than 0.5 mg/kg/h maintained by subcutaneously implanted osmotic minipumps, specific binding of 3H-spiroperidol was reduced in rat striatum and frontal cortex as previously reported. These effects were dose-dependent at low