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P314 Effects of long-term estrogen replacement therapy on bone turnover in periarticular tibial osteophytes in surgically postmenopausal cynomolgus monkeys


Book ID
114349256
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
116 KB
Volume
13
Category
Article
ISSN
1063-4584

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## Abstract ## Objective To determine the effects of long‐term estrogen replacement therapy (ERT) on the severity of osteoarthritis (OA) of the knee joint in surgically postmenopausal (bilaterally ovariectomized) female monkeys. A secondary aim was to evaluate the effect of soy phytoestrogen (SPE)