Clinically reported heterozygous mutatio
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Eng-King Tan; F. Shaffra Refai; Mobin Siddique; Karen Yap; Patrick Ho; Stephanie
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Article
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2009
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John Wiley and Sons
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English
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Mutations in the gene encoding phosphatase and tensin homolog (PTEN)-induced kinase 1 (PINK1) have been associated with the loss of dopaminergic neurons characteristic of familial and sporadic Parkinson disease. We developed an in vitro system of stable human dopaminergic neuronal cell lines coexpre