P3.049 b2 Adrenergic receptor activation induces microglial NADPH oxidase activation and dopaminergic neurotoxicity through an ERK-dependent/protein kinase A-independent pathway

β2 Adrenergic receptor activation induce

β2 Adrenergic receptor activation induces microglial NADPH oxidase activation and dopaminergic neurotoxicity through an ERK-dependent/protein kinase A-independent pathway

✍ Li Qian; Xiaoming Hu; Dan Zhang; Amanda Snyder; Hung-Ming Wu; Yachen Li; Belinda 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 347 KB

## Abstract Activation of the β2 adrenergic receptor (β2AR) on immune cells has been reported to possess anti‐inflammatory properties, however, the pro‐inflammatory properties of β2AR activation remain unclear. In this study, using rat primary mesencephalic neuron‐glia cultures, we report that salm