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P.3.039 - Regulation of AP-1 transcription complex in the CNS by antipsychotics

✍ Scribed by P. Rogue; A.N. Malviya; G. Vincendon

Book ID
119176585
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
158 KB
Volume
6
Category
Article
ISSN
0924-977X

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## Abstract We have previously reported that human matrix metalloproteinase‐1 (MMP1) is a __p53__ target gene subject to down‐regulation (Sun et al. [1999]: J Biol Chem 274:11535–11540]. In the present study, we demonstrate that the down‐regulation of the human βˆ’83MMP1 promoter fragment by p53 was