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P3.028 Analysis of the LRRK2 p.G2019S mutation in Colombian Parkinson's disease patients

✍ Scribed by A.F. Duque Rodríguez; J.J. Yunis Londoño; H. Arboleda Granados; W. Fernández Escobar; G. Arboleda Bustos

Book ID
117753795
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
58 KB
Volume
15
Category
Article
ISSN
1353-8020

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## Abstract Mutations in the Leucine‐Rich Repeat Kinase 2 gene (__LRRK2__) are mainly responsible for idiopathic Parkinson's disease (PD) with either a dominant pattern of transmission or a sporadic occurrence due to the reduced penetrance. A majority of __LRRK2__ kindreds demonstrate an extremely