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p300gene alterations in intestinal and diffuse types of gastric carcinoma

✍ Scribed by Naoki Koshiishi; Ja-Mun Chong; Tomoki Fukasawa; Rie Ikeno; Yukiko Hayashi; Nobuaki Funata; Hideo Nagai; Michiko Miyaki; Yoshiro Matsumoto; Masashi Fukayama

Publisher
Springer
Year
2004
Tongue
English
Weight
269 KB
Volume
7
Category
Article
ISSN
1436-3291

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## Abstract All histologically confirmed gastric cancer cases diagnosed during the periods 1940–1944 and 1960–1964 at the Hartford Hospital were classified into three groups: intestinal, difuse and others, according to a modified LaurΓ©n's classification. A reduction in the frequency of intestinal t

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## Background: It has been suggested that cyclin-dependent kinase inhibitors (cdkis), including p16 and p15, are tumor suppressor genes. alterations of cdkis have been found in most types of cancer. however, little is known about the status of p16 and p15 genes, including methylation of the promote