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P.300 Porphyria cutanea tarda and hepatitis C infection: a case report

✍ Scribed by F.M. Tengan; N.P. Cavalheiro; K.Y. Ibrahim; C.E. Melo; K.T. Miyaji; E.S.A. Araujo; A.A. Barone

Book ID
117770516
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
137 KB
Volume
36
Category
Article
ISSN
1386-6532

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Porphyria cutanea tarda and hepatitis C
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We studied the prevalence of hepatitis C virus (HCV) infection in 20 Japanese patients with sporadic-type porphyria cutanea tarda (PCT). Seventeen of the 20 patients (85%) had anti-HCV antibodies. Biochemical remission was observed in nine patients, six of whom still had positive HCV RNA copies. The

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Porphyria cutanea tarda in human beings is believed to be due to reduced hepatic uroporphyrinogen decarboxylase activity. However, extrinsic factors such as alcohol abuse and drug intake are required for clinical manifestation of the disease. In addition to typical cutaneous lesions, patients with p