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P3-397: Comparative proteomic profiling of mitochondrial proteins in a triple transgenic mouse model of Alzheimer's disease

✍ Scribed by Breen, Gail A.; Chou, Jose; Choudhary, Pankaj; Goodman, Steven R.

Book ID
122506479
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
55 KB
Volume
4
Category
Article
ISSN
1552-5260

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Mitochondrial structural and functional alterations appear to play to an important role in the pathogenesis of Alzheimer's disease (AD). In the present study, we used a quantitative comparative proteomic profiling approach to analyze changes in the mitochondrial proteome in AD. A triple transgenic m