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P3-270: An association study between progranulin gene polymorphisms and Alzheimer's disease

โœ Scribed by Viswanathan, Jayashree; Helisalmi, Seppo; Haapasalo, Annakaisa; Soininen, Hilkka; Hiltunen, Mikko

Book ID
123579310
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
56 KB
Volume
4
Category
Article
ISSN
1552-5260

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An association study between granulin ge
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โœ Jayashree Viswanathan; Petra Mรคkinen; Seppo Helisalmi; Annakaisa Haapasalo; Hilk ๐Ÿ“‚ Article ๐Ÿ“… 2009 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 103 KB ๐Ÿ‘ 2 views

## Abstract Granulin protein plays an important role in neurite outgrowth and neuronal survival. Recently, it was shown that mutations in __granulin__ (__GRN__) gene cause tauโ€negative frontotemporal dementia supporting the idea that granulin is involved in neurodegeneration. Here we have investiga