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P2Y2 receptor-mediated proliferation of C6 glioma cells via activation of Ras/Raf/MEK/MAPK pathway

✍ Scribed by Ming-Tze Tu; Shue-Fen Luo; Chuan-Chawn Wang; Chin-Sung Chien; Chi-Tso Chiu; Chih-Chung Lin; Chuen-Mao Yang


Book ID
110004885
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
587 KB
Volume
129
Category
Article
ISSN
0007-1188

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## Abstract Phenotypic remodeling of Schwann cells is required to ensure successful regeneration of damaged peripheral axons. After nerve damage, Schwann cells produce an over 100‐fold increase in metalloproteinase‐9 (MMP‐9), and therapy with an MMP inhibitor increases the number of resident (but n