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P2Y1 Receptor-evoked Glutamate Exocytosis from Astrocytes

โœ Scribed by Domercq, Maria; Brambilla, Liliana; Pilati, Ethel; Marchaland, Julie; Volterra, Andrea; Bezzi, Paola


Book ID
124055184
Publisher
The American Society for Biochemistry and Molecular Biology
Year
2006
Tongue
English
Weight
987 KB
Volume
281
Category
Article
ISSN
0021-9258

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Astrocytes are thought to control extracellular glutamate concentrations ([Glu] o ) in the brain, thereby protecting neurons from excitotoxic injury. We investigated the effects of metabotropic glutamate receptor (mGluR) agonists on glutamate transport and [Glu] o in primary hippocampal astrocytic c