## Abstract We explored the possibility of hetero‐oligomerization between G~i/o~ protein‐coupled A~1~ adenosine receptor (A~1~R) and G~q~ protein‐coupled P2Y~1~ receptor (P2Y~1~R) in transfected cultured cells by a new bioluminescence resonance energy transfer technology (BRET^2^) in addition to in
✦ LIBER ✦
P2Y receptors in brain astroglial cells: Identification of a gliotic P2Y receptor coupled to activation of a calcium-independent ras/ERK1/2 pathway
✍ Scribed by Roberta Brambilla; Joseph T. Neary; Marta Fumagalli; Lorenzo Cottini; Flaminio Cattabeni; Paul R. Schiller; Maria P. Abbracchio
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 239 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0272-4391
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## Abstract The effects of P2Y2 purinoceptor activation on c‐Fos expression and the signaling pathways evoked by extracellular ATP/UTP in HeLa cells were investigated. We found that P2Y2 activation induced c‐Fos protein and phosphorylated the extracellular signal‐regulated kinases 1 and 2 (ERK1/2).