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P2X7 receptor gene polymorphism analysis in rheumatoid arthritis

✍ Scribed by A. Al-Shukaili; J. Al-Kaabi; B. Hassan; T. Al-Araimi; M. Al-Tobi; M. Al-Kindi; A. Al-Maniri; A. Al-Gheilani; A. Al-Ansari


Book ID
114831769
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
95 KB
Volume
38
Category
Article
ISSN
1744-3121

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## Abstract ## Objective Recent findings suggest that interferon regulatory factor 5 (IRF‐5) may play a crucial role in several cellular processes, including the transcription of genes for inflammatory cytokines. Two genetic variants of the __IRF5__ gene (rs2004640 in exon 1 and rs2280714 in the 3