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P2X7 nucleotide receptor: Modulation of LPS-induced macrophage signaling and mediator production

✍ Scribed by Jyoti J. Watters; Julie A. Sommer; Philip L. Fisette; Zachary A. Pfeiffer; Mini Aga; Usha Prabhu; Alma N. Guerra; Loren C. Denlinger; Paul J. Bertics


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
247 KB
Volume
53
Category
Article
ISSN
0272-4391

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## Abstract ATP is the dominant messenger for astrocyte‐to‐astrocyte calcium‐mediated communication. Definition of the exact ATP/P2 receptors in astrocytes and of their coupling to intracellular calcium ([Ca^2+^]~i~) has important implications for brain physiology and pathology. We show that, with