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P2X4 receptor regulates P2X7 receptor-dependent IL-1β and IL-18 release in mouse bone marrow-derived dendritic cells

✍ Scribed by Sakaki, Hayato; Fujiwaki, Takuya; Tsukimoto, Mitsutoshi; Kawano, Ayumi; Harada, Hitoshi; Kojima, Shuji

Book ID
122904276
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
561 KB
Volume
432
Category
Article
ISSN
0006-291X

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## Abstract Extracellular nucleotide di‐ and triphosphates such as ATP and ADP mediate their effects through purinergic P2 receptors belonging to either the metabotropic P2Y or the ionotropic P2X receptor family. The P2X~7~R is a unique member of the P2X family, which forms a pore in response to li