𝔖 Bobbio Scriptorium
✦   LIBER   ✦

P2A23 - Design of CYP 2C18 and 2C19 substrates based on hydroxylation of 2-aroyl-thiophenes

✍ Scribed by C. Minoletti; A. Mancy; T. Ha-Duong; S. Dijols; P.M. Dansette; D. Mansuy


Book ID
119540133
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
142 KB
Volume
95
Category
Article
ISSN
0378-4274

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Homology modeling and substrate binding
✍ Vilia Ann Payne; Yan-Tyng Chang; Gilda H. Loew πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 583 KB

It is well established that the variable binding-site architecture and composition of the P450 metabolizing heme proteins are major modulators of substrate and product specificity. Even the three closely related human liver isozymes, CYP2C9, CYP2C18, and CYP2C19, do not share all substrates and do n