P299 Is neoadjuvant chemotherapy in breast cancer increasing?
✍ Scribed by B. Sancho Perez; M. Gallego; M.C. Sanz; M.L. Arroyo; S. Aragón; M. Blanco; P. Manosalvas; E. Ciruelos; L. Manso; J.M. Hérnandez
- Book ID
- 114316636
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 36 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0960-9776
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Optimal management of locally advanced breast cancer is controversial. Claims of superiority for neoadjuvant systemic therapy are based on comparisons with outdated historical control groups who received no chemotherapy. Between 1978 and 1987, 118 patients with locally advanced breast cancer underwe
Thirty-eight patients with locally advanced breast cancer (Stage HI) were treated over a 3-year period. All patients initially received two cycles of CMF (cyclophosphamide, 100 mg/m2 p.0. dl-14; methotrexate 40mg/m2 intravenously (iv), d l and d8., 5 Fluorouracil 500 mg/m2 iv d l and d8). They were