p27 Modulates Cell Cycle Progression and Chemosensitivity in Human Malignant Glioma
β Scribed by Ulrike Naumann; Simone Weit; Lorenz Rieger; Richard Meyermann; Michael Weller
- Book ID
- 115584227
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 434 KB
- Volume
- 261
- Category
- Article
- ISSN
- 0006-291X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract BRCA1 is a multifunctional tumorβsuppressive protein. Many functional aspects of BRCA1 are not fully understood. We used a shRNA approach to probe the function of BRCA1 in human breast cancer cells. Knocking down BRCA1 expression by shRNA in the wildβtype BRCA1 human breast cancer MCFβ7
Connective tissue growth factor (CTGF) is a 38-kDa cysteine-rich peptide, whose synthesis and secretion are selectively induced by transforming growth factor beta (TGF-β€) in connective tissue cells. Previous studies have demonstrated that CTGF functions as a downstream mediator of TGF-β€ mitogenic ac
Proliferation of six established human melanoma cell lines was inhibited after treatment for 1 h with a high dose of glucocorticoid. Four of the lines with the capacity of colony formation were used to quantify final plating efficiency. Specific glucocorticoid binding sites in these cell lines range