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p27 downregulation and metallothionein overexpression in gastric cancer patients are associated with a poor survival rate

✍ Scribed by Gennaro Galizia; Francesca Ferraraccio; Eva Lieto; Michele Orditura; Paolo Castellano; Vincenzo Imperatore; Giovanni La Manna; Margherita Pinto; Fortunato Ciardiello; Anna La Mura; Ferdinando De Vita


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
173 KB
Volume
93
Category
Article
ISSN
0022-4790

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Promoter methylation of the Wnt/Ξ²-cateni
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## Abstract ## BACKGROUND: Abnormal activation of the Wnt/β‐catenin signaling pathway is common and critical in the pathogenesis of digestive cancers. In this study, the authors investigated the promoter methylation of the dickkopf homolog 3 gene __Dkk‐3__ in these cancers and its prognostic signi