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P258 EFFECTS OF METFORMIN IN PARAOXONASE-1 DEFICIENT MICE

✍ Scribed by García-Heredia, A.; Fort, I.; Riera-Borrull, M.; Rodríguez-Gallego, E.; Hernández-Aguilera, A.; Luciano-Mateo, F.; Fernández-Arroyo, S.; Abengochea, A.; Mariné-Casadó, R.; Guirro, M.; Camps, J.

Book ID
122250055
Publisher
Elsevier Science
Year
2014
Tongue
English
Weight
63 KB
Volume
60
Category
Article
ISSN
0168-8278

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## Abstract Mice with disrupted germline __p53__ alleles have been engineered by us and others and have been shown to have enhanced susceptibility to spontaneous tumors of various types. We monitored a large number of __p53__‐deficient mice(__p53__+/− and __p53__−/−) and their wild‐type littermates