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P256 electroperturbation of the human skin barrier in vitro: effects on stratum corneum resistance, capacitance, lipid ordering and ultrastructure

✍ Scribed by Craane-van Hinsberg, W.H.M.; Spies, F.; Gooris, G.S.; Bouwstra, J.A.; Verhoef, J.C.; Junginger, H.E.; Boddé, H.E.

Book ID
122833492
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
124 KB
Volume
2
Category
Article
ISSN
0928-0987

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In transdermal iontophoresis, drugs can be driven across the skin by electrorepulsion, but their transport can also be enhanced by electrical perturbation of the skin barrier. Our objective was to study perturbing effects of electrical current on human stratum corneum lipid fine structure combining