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p21WAF1/Cip1 is not involved in kainic acid-induced apoptosis in murine cerebellar granule cells

✍ Scribed by Ester Verdaguer; Elvira G. Jordà; Anna Maria Canudas; Andrés Jiménez; Jaume Folch; Victor Rimbau; Mercè Pallàs; Antoni Camins

Book ID: 113500165
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 376 KB
Volume: 1030
Category: Article
ISSN: 0006-8993
DOI: 10.1016/j.brainres.2004.09.052

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## Abstract Butyric acid is well recognized as a histone deacetylase (HDAC) inhibitor, and changes in histone acetylation are thought to alter gene expression. The mechanism by which sodium butyrate (NaB) induces p21^WAF1/CIP1^, a critical gene involved in the antiproliferative effect of NaB, was s