p21WAF1 gene promoter is epigenetically silenced by CTIP2 and SUV39H1

Homeobox gene HOPX is epigenetically sil

Homeobox gene HOPX is epigenetically silenced in human uterine endometrial cancer and suppresses estrogen-stimulated proliferation of cancer cells by inhibiting serum response factor

✍ Shinichiro Yamaguchi; Kazuo Asanoma; Tomoka Takao; Kiyoko Kato; Norio Wake 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 French ⚖ 687 KB

## Abstract __HOPX (homeodomain only protein X__) is a newly identified homeobox gene whose loss of expression has been reported for several types of neoplasm. Although we found most human uterine endometrial cancers (HEC) defective in HOPX expression, genetic mutations in the __HOPX__ gene were un