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p21Cip1/Waf1/Sdi1 protects against hyperoxia by maintaining expression of Bcl-XL

โœ Scribed by Rhonda J. Staversky; Peter F. Vitiello; Sean C. Gehen; Christopher E. Helt; Arshad Rahman; Peter C. Keng; Michael A. O'Reilly


Book ID
113630000
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
528 KB
Volume
41
Category
Article
ISSN
0891-5849

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โœ J H Albrecht; A H Meyer; M Y Hu ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 817 KB

WAF1/Cip1/Sdi1 (p21) is the prototype of a family of proteins that inhibit cyclin-dependent kinases and regulate cell cycle progression in eukaryotic cells. In addition to normal cell cycle progression, p21 is involved in growth suppression mediated by p53 and transforming growth factor beta (TGFbet