𝔖 Bobbio Scriptorium
✦   LIBER   ✦

P2.19: A strategy for the analysis of complex genotype-phenotype relationships

✍ Scribed by Karla Köpke


Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
77 KB
Volume
46
Category
Article
ISSN
0323-3847

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Application of robust pedigree analysis
✍ Loesch, D.Z. ;Huggins, R.M. ;Taylor, A.K. 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 147 KB 👁 2 views

## Abstract Relationships between the fragile X dynamic mutation and palmar and finger epidermal ridge measures were assessed using a robust modification of the maximum likelihood estimators for pedigree data. A total of 34 extended families affected with fragile X syndrome were used. Phenotypic tr

Genotype–phenotype analysis of the branc
✍ Jeff M. Milunsky; Tom M. Maher; Geping Zhao; Zhenyuan Wang; John B. Mulliken; Da 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 203 KB 👁 2 views

## Abstract Branchio‐oculo‐facial syndrome (BOFS; OMIM#113620) is a rare autosomal dominant craniofacial disorder with variable expression. Major features include cutaneous and ocular abnormalities, characteristic facies, renal, ectodermal, and temporal bone anomalies. Having determined that mutati

Genotype–phenotype relationships in an i
✍ P. Eriksson; S. Jormsjö-Pettersson; A. R. Brady; H. Deguchi; A. Hamsten; J. T. P 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 105 KB 👁 2 views

## Abstract ## Background The aim of the study was to investigate the effect of functional polymorphisms in promoters of matrix metalloproteinase (MMP) 2, MMP-3, MMP-9, MMP-12 and plasminogen activator inhibitor (PAI) 1 genes on the growth rate of small abdominal aortic aneurysms (AAA). ## Method

The use of phenome-wide association stud
✍ S.A. Pendergrass; K. Brown-Gentry; S.M. Dudek; E.S. Torstenson; J.L. Ambite; C.L 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 441 KB 👁 1 views

The field of phenomics has been investigating network structure among large arrays of phenotypes, and genome-wide association studies (GWAS) have been used to investigate the relationship between genetic variation and single diseases/ outcomes. A novel approach has emerged combining both the explora

Characterization of genotype–phenotype r
✍ Nigel P.S. Crawford; Daniel W. Colliver; Alisa A. Funke; Michael N. Young; Scott 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 187 KB

The classification of ulcerative colitis (UC), Crohn disease (CD), and indeterminate colitis (IC) as forms of inflammatory bowel disease (IBD) is based on clinical, radiological, and histological criteria. The genetic basis of IBD is well founded, and susceptibility loci have been identified on seve