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P.2.036 Polymorphisms of dopamine D2 and D4 receptors genes as predictors of therapeutic response to haloperidol and clozapine

✍ Scribed by P. Vinuesa Gómez; E. Grasa

Book ID
119577026
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
147 KB
Volume
13
Category
Article
ISSN
0924-977X

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## Abstract We have examined the hypothesis that a variable number of tandem repeats in the third cytoplasmic loop of the dopamine D4 receptor influences clinical response to clozapine using a sample of 189 schizophrenic patients. Alleles of the 48‐bp repeat, which range from two to ten copies in t