P202 - Hemochromatosis and HLA: New evidence and methods
β Scribed by LM Calandro; M Grote; MP Roth; LF Barcellos; D Baer; G Sensabaugh; G Thomson; W Klitz
- Book ID
- 116114609
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 146 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0198-8859
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π SIMILAR VOLUMES
We previously reported five families with primary, genetic (idiopathic) hemochromatosis in whom HLA typing of subjects indicated that a homozygous-heterozygous mating had almost certainly occurred and in whom inheritance of the disease trait was best explained by an autosomal recessive mode of inher
Hereditary hemochromatosis (HH), which affects some 1 in 400 and has an estimated carrier frequency of 1 in 10 individuals of Northern European descent, results in multi-organ dysfunction caused by increased iron deposition, and is treatable if detected early. Using linkage-disequilibrium and full h