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P2 purinoceptor-mediated inositol phosphate formation in relation to cytoplasmic calcium in DDT1 MF-2 smooth muscle cells

✍ Scribed by Ben Hoiting; Areles Molleman; Marry Duin; Adriaan den Hertog; Adriaan Nelemans

Book ID: 113398116
Publisher: Elsevier Science
Year: 1990
Tongue: English
Weight: 658 KB
Volume: 189
Category: Article
ISSN: 0922-4106
DOI: 10.1016/0922-4106(90)90227-o

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## Abstract Cannabinoid CB~1~‐receptor stimulation in DDT~1~ MF‐2 smooth muscle cells induces a rise in [Ca^2+^]~i~, which is dependent on extracellular Ca^2+^ and modulated by thapsigargin‐sensitive stores, suggesting capacitative Ca^2+^ entry (CCE), and by MAP kinase. Non‐capacitative Ca^2+^ entr