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P2-purinergic agonists activate phospholipase C in a guanine nucleotide- and Ca2+-dependent manner in FRTL-5 thyroid cell membranes

✍ Scribed by Fumikazu Okajima; Koichi Sato; Yoichi Kondo


Book ID
115922099
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
301 KB
Volume
253
Category
Article
ISSN
0014-5793

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Extracellular ATP-mediated phospholipase
✍ Elina Ekokoski; Benoit DuguΓ©; Minna Vainio; Petri J. Vainio; Kid TΓΆrnquist πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 234 KB πŸ‘ 2 views

We investigated the mechanism of phospholipase A 2 (PLA 2 ) activation in response to the P2 receptor agonist ATP in rat thyroid FRTL-5 cells. The PLA 2 activity was determined by measuring the release of [ 3 H]-arachidonic acid (AA) from prelabeled cells. ATP evoked a dose-and time-dependent AA rel